'
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
5
USERS' SCORE
Excellent
Based on 104 Reviews
9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
50 mcg (2,000 IU)
250%

Top Medical Research Studies

2
Vitamin D3 ineffective for CFS
Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial.
Directly tests treatment effectiveness
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More
8
Beta-glucan shows cognitive improvements
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Vitamin D3 effects unclear
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More

Most Useful Reviews

9.5
Boosted immune system
Very good vitamins at a reasonable price. The whole family takes one small capsule daily with food. I've noticed a significant reduction in chronic fatigue syndrome and an improvement in my health, particularly after illnesses. Vitamin D3 supports recovery, strengthens bones, boosts muscle strength, and enhances mood. I've been taking it consistently and find it essential for my wellbeing, especially during the winter months.
Read More
8.8
Improved vitamin levels
As someone who faced low vitamin D levels, I can attest to its role in combating chronic fatigue syndrome. After six months of taking Vitamin D3, my levels increased from 17 ng/ml to 40 ng/ml. My endocrinologist highlighted its immunomodulatory effects. I consistently take it along with vitamin K2, Omega-3, and lecithin, doing regular blood tests to maintain optimum levels.
Read More
9.5
Eliminated colds
Wonderful vitamins, small capsules taken once daily. I've been using them for four months, and they have alleviated my chronic fatigue syndrome and helped me avoid colds.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
5
8
Beta-glucan shows cognitive improvements
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Vitamin D3 effects unclear
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More
2
Vitamin D3 ineffective for CFS
Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial.
Directly tests treatment effectiveness
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 104 Reviews
9
9.5
Boosted immune system
Very good vitamins at a reasonable price. The whole family takes one small capsule daily with food. I've noticed a significant reduction in chronic fatigue syndrome and an improvement in my health, particularly after illnesses. Vitamin D3 supports recovery, strengthens bones, boosts muscle strength, and enhances mood. I've been taking it consistently and find it essential for my wellbeing, especially during the winter months.
Read More
9.5
Eliminated colds
Wonderful vitamins, small capsules taken once daily. I've been using them for four months, and they have alleviated my chronic fatigue syndrome and helped me avoid colds.
9.5
Strengthened mood
Wonderful vitamins that I've been taking for four months. They have helped me overcome chronic fatigue syndrome, and I haven't felt ill at all.
9.5
Fewer sick days
Since beginning vitamin D, I've had less chronic fatigue syndrome and have not fallen ill throughout winter. I believe this is directly related to my vitamin D intake. Energy levels have also improved, and I encourage anyone in similar latitudes to consider taking it.
9.5
Enhanced energy levels
Marvellous! I suffered from chronic fatigue syndrome and was perpetually tired. This vitamin has significantly improved my energy and overall wellbeing. After a month, I feel revitalised and at peace!
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